Dynamic and static conditioning pressures evoke equivalent rapid resetting in rat aortic baroreceptors.
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چکیده
منابع مشابه
Dynamic and static conditioning pressures evoke equivalent rapid resetting in rat aortic baroreceptors.
A recent study suggested that exposure of carotid sinus baroreceptors to pulsatile pressures for a period of minutes can decrease the static threshold pressure at which they begin to discharge; that is, the exposure can sensitize baroreceptors. Another study found that the rapid resetting of carotid sinus baroreceptors to elevated conditioning pressures was reduced or eliminated by pulsatile co...
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Stimulus-response curves of aortic baroreceptors constructed by alternately increasing and decreasing pressure from a normal baseline or set-point differ from curves constructed by varying pressure in one direction only from an abnormally high or low pressure. In anesthetized dogs we recorded impulses from aortic baroreceptors with myelinated fibers, using a pressurized reservoir to control mea...
متن کاملRat Aortic Baroreceptors
Changes in conditioning mean arterial pressure (cMAP) selectively alter the set point of arterial baroreceptors and baroreflexes without affecting gain. Changes in smooth muscle tone at constant cMAPs shift the pressure-discharge curves of aortic baroreceptors in a similar manner. Using an in vitro preparation of the rat aortic arch, we tested whether near maximal changes in smooth muscle tone ...
متن کاملRapid resetting of the baroreceptors in renal hypertensive rats.
The characteristics and extent of rapid or acute resetting of the aortic baroreceptors were studied in long-term renal hypertensive rats during 30 minutes of sustained hypertension produced by phenylephrine infusion. The aortic baroreceptors of hypertensive rats exhibited complete resetting to hypertension because during the control period the systolic threshold pressure for activation of the b...
متن کاملAntihypertensive Drugs Distinctly Modulate the Rapid Resetting of the Baroreceptors
We investigated the distinct ability of various antihypertensive drugs to modulate the extent (%) of rapid (15 minutes) resetting of the baroreceptors of normotensive rats to hypertensive levels. In one protocol, hemorrhage produced a complete resetting to hypotension in rats chronically treated (6 days) with captopril. Also, hemorrhage produced only partial resetting in rats acutely treated (1...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 1990
ISSN: 0009-7330,1524-4571
DOI: 10.1161/01.res.67.2.303